Alpha-glucosidase Therapy Center

David Joffe, BSPharm, CDE  Brittany Davis, Pharm D Candidate, Presbyterian College School of Pharmacy The molecular mechanisms linking fatty acids to GLP-1 secretion from gut endocrine cells remain incompletely understood. Hirasawa and colleagues have identified a GPCR, designated GPR120 that serves as a receptor for fatty acids on gut endocrine cells. …

Acarbose treatment shows major benefits for type 2s…. 

Acarbose is similar to metformin in efficacy in new study…. 

Anne Peters, MD, and Lori Laffel, MD, MPH, Editors Jane Lee Chiang, MD, Managing Editor Jeremy Hodson Pettus, MD, and Steven Edelman, MD  GLP-1 AGONISTS The incretin effect was discovered after experiments found that administration of oral glucose resulted in an increased insulin secretion compared to the same amount of …

AACE calls for a new guideline based on a tailored approach to treating type 2 diabetes while maintaining the use of an algorithm-based model…. Alan Garber, MD, PhD, of Baylor College of Medicine in Houston, and colleagues reported in Endocrine Practice and at the AACE meeting that, the new recommendations …

Scientists have found compounds that inhibit enzymes responsible for carbohydrate absorption and assimilation similar to the alpha-glucosidase inhibitors. And that could mean a tasty way to help people with diabetes decrease their blood sugar….

By Richard S. Beaser, M.D., and Richard Jackson, MD     The changes that have occurred in the treatment of diabetes since the first general use of insulin in 1922 have constituted one of the most exciting chapters in the history of medicine.

The top three drugs for the reduction of A1c levels are biphasic insulin, glucagon-like peptide 1 (GLP-1) analogs, and….  The top 3 drugs for the reduction of A1c levels are biphasic insulin, glucagon-like peptide 1 (GLP-1) analogs, and basal insulin. Although most oral antidiabetic drugs had a similar effect on …

Edited by Trisha Dunning AM, RN, MEd, PhD, CDE, FRCNA and Glenn Ward MBBS, BSc, DPhil (Oxon), FRACP, FRCPath   Mr. KM was referred to a diabetes center by his GP. Mr. KM is a 77-year-old man who has had type 2 diabetes for 17 years: current HbA1c 9.5%; random …

Sheri Colberg, Ph.D., FACSM, has been helping patients with diabetes successfully increase physical activity for many years and has written numerous books that patients and clinicians use. Most of her work recently has been about insulin and exercise, but many of you have written me to ask, “What about oral …